[(123)I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer

Poly(adenosine diphosphate ribose) polymerase (PARP) has emerged as an effective therapeutic strategy against cancer that targets the DNA damage repair enzyme. PARP-targeting compounds radiolabeled with an Auger electron–emitting radionuclide can be trapped close to damaged DNA in tumor tissue, wher...

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Detalles Bibliográficos
Autores principales: Chan, Chung Ying, Chen, Zijun, Guibbal, Florian, Dias, Gemma, Destro, Gianluca, O’Neill, Edward, Veal, Mathew, Lau, Doreen, Mosley, Michael, Wilson, Thomas C., Gouverneur, Véronique, Cornelissen, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2023
Materias:
Basic Science Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690119/
https://www.ncbi.nlm.nih.gov/pubmed/37770109
http://dx.doi.org/10.2967/jnumed.123.265429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690119/
https://www.ncbi.nlm.nih.gov/pubmed/37770109
http://dx.doi.org/10.2967/jnumed.123.265429

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