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[(123)I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer
Poly(adenosine diphosphate ribose) polymerase (PARP) has emerged as an effective therapeutic strategy against cancer that targets the DNA damage repair enzyme. PARP-targeting compounds radiolabeled with an Auger electron–emitting radionuclide can be trapped close to damaged DNA in tumor tissue, wher...
Autores principales: | Chan, Chung Ying, Chen, Zijun, Guibbal, Florian, Dias, Gemma, Destro, Gianluca, O’Neill, Edward, Veal, Mathew, Lau, Doreen, Mosley, Michael, Wilson, Thomas C., Gouverneur, Véronique, Cornelissen, Bart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Nuclear Medicine
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690119/ https://www.ncbi.nlm.nih.gov/pubmed/37770109 http://dx.doi.org/10.2967/jnumed.123.265429 |
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