ATM Mutations Associate with Distinct Co-Mutational Patterns and Therapeutic Vulnerabilities in NSCLC

PURPOSE: Ataxia-telangiectasia mutated (ATM) is the most frequently mutated DNA damage repair gene in non–small cell lung cancer (NSCLC). However, the molecular correlates of ATM mutations and their clinical implications have not been fully elucidated. EXPERIMENTAL DESIGN: Clinicopathologic and geno...

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Detalles Bibliográficos
Autores principales: Vokes, Natalie I., Galan Cobo, Ana, Fernandez-Chas, Margarita, Molkentine, David, Treviño, Santiago, Druker, Vitaly, Qian, Yu, Patel, Sonia, Schmidt, Stephanie, Hong, Lingzhi, Lewis, Jeff, Rinsurongkawong, Waree, Rinsurongkawong, Vadeerat, Lee, J. Jack, Negrao, Marcelo V., Gibbons, Don L., Vaporciyan, Ara, Le, Xiuning, Wu, Jia, Zhang, Jianjun, Rigney, Una, Iyer, Sonia, Dean, Emma, Heymach, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690143/
https://www.ncbi.nlm.nih.gov/pubmed/37733794
http://dx.doi.org/10.1158/1078-0432.CCR-23-1122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690143/
https://www.ncbi.nlm.nih.gov/pubmed/37733794
http://dx.doi.org/10.1158/1078-0432.CCR-23-1122

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