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Progressive degeneration in a new Drosophila model of Spinocerebellar Ataxia type 7

Spinocerebellar ataxia type 7 (SCA7) is a progressive neurodegenerative disorder resulting from abnormal expansion of polyglutamine (polyQ) in its disease protein, ataxin-7 (ATXN7). ATXN7 is part of Spt-Ada-Gcn5 acetyltransferase (SAGA), an evolutionarily conserved transcriptional coactivation compl...

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Detalles Bibliográficos
Autores principales:	Sujkowski, Alyson L., Ranxhi, Bedri, Prifti, Matthew V., Alam, Nadir, Todi, Sokol V., Tsou, Wei-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690306/ https://www.ncbi.nlm.nih.gov/pubmed/38045332 http://dx.doi.org/10.21203/rs.3.rs-3592641/v1

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