Cationic peptides erase memories by removing synaptic AMPA receptors through endophilin-mediated endocytosis

Administration of the Zeta Inhibitory Peptide (ZIP) interferes with memory maintenance and long-term potentiation (LTP). However, mice lacking its putative target, the protein kinase PKMz, exhibit normal learning and memory as well as LTP, making ZIP’s mechanism unclear. Here, we show that ZIP disru...

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Detalles Bibliográficos
Autores principales: Beier, Kevin, Stokes, Eric, Zhuang, Yinyin, Toledano, Michael, Vasquez, Jose, Azouz, Ghalia, Hui, May, Tyler, Isabella, Shi, Xiaoyu, Aoto, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690331/
https://www.ncbi.nlm.nih.gov/pubmed/38045269
http://dx.doi.org/10.21203/rs.3.rs-3559525/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690331/
https://www.ncbi.nlm.nih.gov/pubmed/38045269
http://dx.doi.org/10.21203/rs.3.rs-3559525/v1

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