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Epigenetic regulation limits competence of pluripotent stem cell‐derived oocytes

Recent studies have reported the differentiation of pluripotent cells into oocytes in vitro. However, the developmental competence of in vitro‐generated oocytes remains low. Here, we perform a comprehensive comparison of mouse germ cell development in vitro over all culture steps versus in vivo with...

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Detalles Bibliográficos
Autores principales: Aizawa, Eishi, Ozonov, Evgeniy A, Kawamura, Yumiko K, Dumeau, Charles‐Etienne, Nagaoka, So, Kitajima, Tomoya S, Saitou, Mitinori, Peters, Antoine HFM, Wutz, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690455/
https://www.ncbi.nlm.nih.gov/pubmed/37850882
http://dx.doi.org/10.15252/embj.2023113955