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MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

The Hippo signaling axis is a tumor suppressor pathway that is activated by various extra‐pathway factors to regulate cell differentiation and organ development. Recent studies have reported that autophosphorylation of the core kinase cassette stimulates activation of the Hippo signaling cascade. He...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Jin, Xin, Meng, Junpeng, Guo, Feng, Chen, Taoyu, Zhao, Xiaoyan, Wu, Heshui, Ren, Dianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690468/
https://www.ncbi.nlm.nih.gov/pubmed/37905571
http://dx.doi.org/10.15252/embj.2023114558