Cargando…

Nanoscale organization of the endogenous ASC speck

The NLRP3 inflammasome is a central component of the innate immune system. Its activation leads to formation of the ASC speck, a supramolecular assembly of the inflammasome adaptor protein ASC. Different models, based on ASC overexpression, have been proposed for the structure of the ASC speck. Usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Glück, Ivo M., Mathias, Grusha Primal, Strauss, Sebastian, Rat, Virgile, Gialdini, Irene, Ebert, Thomas Sebastian, Stafford, Che, Agam, Ganesh, Manley, Suliana, Hornung, Veit, Jungmann, Ralf, Sieben, Christian, Lamb, Don C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690566/
https://www.ncbi.nlm.nih.gov/pubmed/38047065
http://dx.doi.org/10.1016/j.isci.2023.108382