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TXNDC12 inhibits lipid peroxidation and ferroptosis

Ferroptosis is a type of regulated cell death characterized by lipid peroxidation and subsequent damage to the plasma membrane. Here, we report a ferroptosis resistance mechanism involving the upregulation of TXNDC12, a thioredoxin domain-containing protein located in the endoplasmic reticulum. The...

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Detalles Bibliográficos
Autores principales: Tang, Lanlan, Yu, Yan, Deng, Wenjun, Liu, Jiao, Wang, Yichun, Ye, Fanghua, Kang, Rui, Tang, Daolin, He, Qingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690572/
https://www.ncbi.nlm.nih.gov/pubmed/38047088
http://dx.doi.org/10.1016/j.isci.2023.108393