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Unleashing the potential of catalytic RNAs to combat mis-spliced transcripts

Human transcriptome can undergo RNA mis-splicing due to spliceopathies contributing to the increasing number of genetic diseases including muscular dystrophy (MD), Alzheimer disease (AD), Huntington disease (HD), myelodysplastic syndromes (MDS). Intron retention (IR) is a major inducer of spliceopat...

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Detalles Bibliográficos
Autores principales: Khalifah, Bashayer A., Alghamdi, Shareefa A., Alhasan, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690607/
https://www.ncbi.nlm.nih.gov/pubmed/38047291
http://dx.doi.org/10.3389/fbioe.2023.1244377