PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Age-related macular degeneration (AMD) is a chronic, progressive retinal disease characterized by an inflammatory response mediated by activated macrophages and microglia infiltrating the inner layer of the retina. In this study, we demonstrate that inhibition of macrophages through Siglec binding i...

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Detalles Bibliográficos
Autores principales: Krishnan, Anitha, Sendra, Victor G., Patel, Diyan, Lad, Amit, Greene, Michelle K., Smyth, Peter, Gallaher, Samantha A., Herron, Úna M., Scott, Christopher J., Genead, Mohamed, Tolentino, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690618/
https://www.ncbi.nlm.nih.gov/pubmed/38045700
http://dx.doi.org/10.3389/fimmu.2023.1237016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690618/
https://www.ncbi.nlm.nih.gov/pubmed/38045700
http://dx.doi.org/10.3389/fimmu.2023.1237016

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