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Circular RNA circSMAD4 regulates cardiac fibrosis by targeting miR-671-5p and FGFR2 in cardiac fibroblasts

Heart failure is a leading cause of death and is often accompanied by activation of quiescent cardiac myofibroblasts, which results in cardiac fibrosis. In this study, we aimed to identify novel circular RNAs that regulate cardiac fibrosis. We applied transverse aortic constriction (TAC) for 1, 4, a...

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Detalles Bibliográficos
Autores principales: Jeong, Anna, Lim, Yongwoon, Kook, Taewon, Kwon, Duk-Hwa, Cho, Young Kuk, Ryu, Juhee, Lee, Yun-Gyeong, Shin, Sera, Choe, Nakwon, Kim, Yong Sook, Cho, Hye Jung, Kim, Jeong Chul, Choi, Yoonjoo, Lee, Su-Jin, Kim, Hyung-Seok, Kee, Hae Jin, Nam, Kwang-Il, Ahn, Youngkeun, Jeong, Myung Ho, Park, Woo Jin, Kim, Young-Kook, Kook, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690640/
https://www.ncbi.nlm.nih.gov/pubmed/38046397
http://dx.doi.org/10.1016/j.omtn.2023.102071