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Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women

BACKGROUND: Catecholamine-stimulated lipolysis is reduced with aging, which may promote adiposity and insulin resistance. Organic cation transporter 3 (OCT3), which is inhibited by estradiol (E2), mediates catecholamine transport into adipocytes for degradation, thus decreasing lipolysis. In this st...

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Detalles Bibliográficos
Autores principales: Ahmed, Fozia, Vranic, Milica, Hetty, Susanne, Mathioudaki, Argyri, Patsoukaki, Vagia, Fanni, Giovanni, Pereira, Maria J, Eriksson, Jan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690730/
https://www.ncbi.nlm.nih.gov/pubmed/37972266
http://dx.doi.org/10.1210/endocr/bqad172