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Correlation of t(14;18) translocation breakpoint site with clinical characteristics in follicular lymphoma

BACKGROUND: t(14;18)(q32;q21) translocation is an important genetic feature of follicular lymphoma resulting in antiapoptotic B-cell lymphoma 2 (BCL2) protein overexpression. On chromosome 18 breakpoint-site variation is high but does not affect BCL2. Breakpoint most commonly occurs at major breakpo...

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Detalles Bibliográficos
Autores principales: Panjan, Matej, Boltezar, Lucka, Novakovic, Srdjan, Kokovic, Ira, Jezersek Novakovic, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690741/
https://www.ncbi.nlm.nih.gov/pubmed/37439703
http://dx.doi.org/10.2478/raon-2023-0030