Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening

[Image: see text] In vitro evolution strategies have been used for >30 years to generate nucleic acid aptamers against therapeutic targets of interest, including disease-associated proteins. However, this process requires many iterative cycles of selection and amplification, which severely restri...

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Detalles Bibliográficos
Autores principales: Lozoya-Colinas, Adriana, Yu, Yutong, Chaput, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690791/
https://www.ncbi.nlm.nih.gov/pubmed/37962593
http://dx.doi.org/10.1021/jacs.3c09497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690791/
https://www.ncbi.nlm.nih.gov/pubmed/37962593
http://dx.doi.org/10.1021/jacs.3c09497

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