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Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening
[Image: see text] In vitro evolution strategies have been used for >30 years to generate nucleic acid aptamers against therapeutic targets of interest, including disease-associated proteins. However, this process requires many iterative cycles of selection and amplification, which severely restri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690791/ https://www.ncbi.nlm.nih.gov/pubmed/37962593 http://dx.doi.org/10.1021/jacs.3c09497 |