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Total Synthesis of Aleutianamine

[Image: see text] Aleutianamine is a recently isolated pyrroloiminoquinone natural product that displays potent and selective biological activity toward human pancreatic cancer cells with an IC(50) of 25 nM against PANC-1, making it a potential candidate for therapeutic development. We report a synt...

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Detalles Bibliográficos
Autores principales: Yu, Hao, Sercel, Zachary P., Rezgui, Samir P., Farhi, Jonathan, Virgil, Scott C., Stoltz, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690800/
https://www.ncbi.nlm.nih.gov/pubmed/37967164
http://dx.doi.org/10.1021/jacs.3c10212