Amyloidogenic light chains impair plasma cell survival

Systemic light chain amyloidosis (AL) is a clonal plasma cell disorder characterized by the deposition of misfolded immunoglobulin light chains (LC) as insoluble fibrils in organs. The lack of suitable models has hindered the investigation of the disease mechanisms. Our aim was to establish AL LC-pr...

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Detalles Bibliográficos
Autores principales: Pick, Marjorie, Lebel, Eyal, Elgavish, Sharona, Benyamini, Hadar, Nevo, Yuval, Hertz, Rachel, Bar-Tana, Jacob, Rognoni, Paola, Merlini, Giampaolo, Gatt, Moshe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Plasma Cell Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690890/
https://www.ncbi.nlm.nih.gov/pubmed/37381778
http://dx.doi.org/10.3324/haematol.2022.282484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690890/
https://www.ncbi.nlm.nih.gov/pubmed/37381778
http://dx.doi.org/10.3324/haematol.2022.282484

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