Effect of two additional doses of intrathecal methotrexate during induction therapy on serious infectious toxicity in pediatric patients with acute lymphoblastic leukemia

Although initial central nervous system (CNS) involvement is rarely detected in childhood acute lymphoblastic leukemia (ALL), risk-adapted CNS-directed therapy is essential for all patients. Treatment intensity depends on the initial CNS status. In the AIEOP-BFM ALL 2009 trial, patients with cytomor...

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Detalles Bibliográficos
Autores principales: Heilmann, Janina, Vieth, Simon, Möricke, Anja, Attarbaschi, Andishe, Barbaric, Draga, Bodmer, Nicole, Colombini, Antonella, Dalla-Pozza, Luciano, Elitzur, Sarah, Izraeli, Shai, Mann, Georg, Niggli, Felix, Silvestri, Daniela, Stary, Jan, Rizzari, Carmelo, Valsecchi, Maria Grazia, Zapotocka, Ester, Zimmermann, Martin, Cario, Gunnar, Schrappe, Martin, Conter, Valentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Acute Lymphoblastic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690925/
https://www.ncbi.nlm.nih.gov/pubmed/37021527
http://dx.doi.org/10.3324/haematol.2022.281788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690925/
https://www.ncbi.nlm.nih.gov/pubmed/37021527
http://dx.doi.org/10.3324/haematol.2022.281788

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