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Antileishmanial effects of γCdcPLI, a phospholipase A(2) inhibitor from Crotalus durissus collilineatus snake serum, on Leishmania (Leishmania) amazonensis

BACKGROUND: Leishmaniasis, a neglected disease caused by the parasite Leishmania, is treated with drugs associated with high toxicity and limited efficacy, in addition to constant reports of the emergence of resistant parasites. In this context, snake serums emerge as good candidates since they are...

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Detalles Bibliográficos
Autores principales: Gonçalves, Marina Neves, Lopes, Daiana Silva, Teixeira, Samuel Cota, Teixeira, Thaise Lara, de Freitas, Vitor, Costa, Tássia Rafaella, Gimenes, Sarah Natalie Cirilo, de Camargo, Isabella Mitie, de Souza, Guilherme, da Silva, Marcelo Santos, Azevedo, Fernanda Van Petten de Vasconcelos, Grego, Kathleen Fernandes, Santos, Luísa Carregosa, Oliveira, Vinícius Queiroz, da Silva, Claudio Vieira, Rodrigues, Renata Santos, Yoneyama, Kelly Aparecida Geraldo, Clissa, Patricia Bianca, Rodrigues, Veridiana de Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690931/
https://www.ncbi.nlm.nih.gov/pubmed/38018570
http://dx.doi.org/10.1590/0074-02760220225