Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis

How the function of the JMJD2D epigenetic regulator is regulated or whether it plays a role in prostate cancer has remained elusive. We found that JMJD2D was overexpressed in prostate tumors, stimulated prostate cancer cell growth and became methylated by SET7/9 on K427. Mutation of this lysine resi...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Ruicai, Kim, Tae-Dong, Jiang, Hanlin, Shin, Sook, Oh, Sangphil, Janknecht, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690936/
https://www.ncbi.nlm.nih.gov/pubmed/38045004
http://dx.doi.org/10.3389/fonc.2023.1295613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690936/
https://www.ncbi.nlm.nih.gov/pubmed/38045004
http://dx.doi.org/10.3389/fonc.2023.1295613

Ejemplares similares