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Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis
How the function of the JMJD2D epigenetic regulator is regulated or whether it plays a role in prostate cancer has remained elusive. We found that JMJD2D was overexpressed in prostate tumors, stimulated prostate cancer cell growth and became methylated by SET7/9 on K427. Mutation of this lysine resi...
Autores principales: | Gu, Ruicai, Kim, Tae-Dong, Jiang, Hanlin, Shin, Sook, Oh, Sangphil, Janknecht, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690936/ https://www.ncbi.nlm.nih.gov/pubmed/38045004 http://dx.doi.org/10.3389/fonc.2023.1295613 |
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