Ex vivo expansion of regulatory T cells from abdominal aortic aneurysm patients inhibits aneurysm in humanized murine model

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease. Studies of human aneurysm tissue demonstrate dense inflammatory cell infiltrates with CD4(+) T cells predominating. Regulatory T cells (Tregs) play an important role in inhibiting pro-inflammatory T cell proliferation, the...

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Detalles Bibliográficos
Autores principales: Suh, Melissa K., Batra, Rishi, Carson, Jeffrey S., Xiong, Wanfen, Dale, Matthew A., Meisinger, Trevor, Killen, Cameron, Mitchell, John, Baxter, B. Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690961/
https://www.ncbi.nlm.nih.gov/pubmed/31980239
http://dx.doi.org/10.1016/j.jvs.2019.08.285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690961/
https://www.ncbi.nlm.nih.gov/pubmed/31980239
http://dx.doi.org/10.1016/j.jvs.2019.08.285

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