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Hybrid-hybrid correction of errors in long reads with HERO

Although generally superior, hybrid approaches for correcting errors in third-generation sequencing (TGS) reads, using next-generation sequencing (NGS) reads, mistake haplotype-specific variants for errors in polyploid and mixed samples. We suggest HERO, as the first “hybrid-hybrid” approach, to mak...

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Detalles Bibliográficos
Autores principales: Kang, Xiongbin, Xu, Jialu, Luo, Xiao, Schönhuth, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690975/
https://www.ncbi.nlm.nih.gov/pubmed/38041098
http://dx.doi.org/10.1186/s13059-023-03112-7