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Neoantigen-targeted TCR-engineered T cell immunotherapy: current advances and challenges

Adoptive cell therapy using T cell receptor-engineered T cells (TCR-T) is a promising approach for cancer therapy with an expectation of no significant side effects. In the human body, mature T cells are armed with an incredible diversity of T cell receptors (TCRs) that theoretically react to the va...

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Detalles Bibliográficos
Autores principales: Pang, Zhi, Lu, Man-man, Zhang, Yu, Gao, Yuan, Bai, Jin-jin, Gu, Jian-ying, Xie, Lu, Wu, Wei-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690996/
https://www.ncbi.nlm.nih.gov/pubmed/38037114
http://dx.doi.org/10.1186/s40364-023-00534-0