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Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsis

BACKGROUND: Sepsis-associated encephalopathy (SAE) is characterized by symptoms of delirium including hallucinations, impaired concentration, agitation, or coma and is associated with poor outcome in the early phase of sepsis. In addition, sepsis survivors often suffer from persisting memory deficit...

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Detalles Bibliográficos
Autores principales: Mein, Nils, von Stackelberg, Nikolai, Wickel, Jonathan, Geis, Christian, Chung, Ha-Yeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691003/
https://www.ncbi.nlm.nih.gov/pubmed/38041192
http://dx.doi.org/10.1186/s12974-023-02975-8