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Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle

BACKGROUND: Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan formula (JDNWF) is a eutherapeutic Chinese medicine formula for ACLF. However,...

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Detalles Bibliográficos
Autores principales: Liang, Jiajun, Wei, Xiaoyi, Hou, Weixin, Wang, Hanjing, Ma, Ruimin, Gao, Yanbin, Du, Yuqiong, Zhang, Qiuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691013/
https://www.ncbi.nlm.nih.gov/pubmed/38037150
http://dx.doi.org/10.1186/s13020-023-00858-x