Cargando…
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle
BACKGROUND: Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan formula (JDNWF) is a eutherapeutic Chinese medicine formula for ACLF. However,...
Autores principales: | Liang, Jiajun, Wei, Xiaoyi, Hou, Weixin, Wang, Hanjing, Ma, Ruimin, Gao, Yanbin, Du, Yuqiong, Zhang, Qiuyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691013/ https://www.ncbi.nlm.nih.gov/pubmed/38037150 http://dx.doi.org/10.1186/s13020-023-00858-x |
Ejemplares similares
-
Network Pharmacology Approach to Explore the Potential Mechanisms of Jieduan-Niwan Formula Treating Acute-on-Chronic Liver Failure
por: Liang, Jiajun, et al.
Publicado: (2020) -
The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats
por: Hou, Weixin, et al.
Publicado: (2021) -
Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro
por: Fang, Peng, et al.
Publicado: (2022) -
Jieduan-Niwan Formula Reduces Liver Apoptosis in a Rat Model of Acute-on-Chronic Liver Failure by Regulating the E2F1-Mediated Intrinsic Apoptosis Pathway
por: Yang, Wenlong, et al.
Publicado: (2019) -
Bioinformatics analyses of potential ACLF biological mechanisms and identification of immune-related hub genes and vital miRNAs
por: Liang, Jiajun, et al.
Publicado: (2022)