Musashi-2 Deficiency Triggers Colorectal Cancer Ferroptosis by Downregulating the MAPK Signaling Cascade to Inhibit HSPB1 Phosphorylation

BACKGROUND: Musashi-2 (MSI2) is a critical RNA-binding protein (RBP) whose ectopic expression drives the pathogenesis of various cancers. Accumulating evidence suggests that inducing ferroptosis of tumor cells can inhibit their malignant biological behavior as a promising therapeutic approach. Howev...

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Detalles Bibliográficos
Autores principales: Meng, Xiaole, Peng, Xiao, Ouyang, Wanxin, Li, Hui, Na, Risi, Zhou, Wenting, You, Xuting, Li, Yuhuan, Pu, Xin, Zhang, Ke, Xia, Junjie, Wang, Jie, Zhuang, Guohong, Tang, Huamei, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691036/
https://www.ncbi.nlm.nih.gov/pubmed/38041016
http://dx.doi.org/10.1186/s12575-023-00222-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691036/
https://www.ncbi.nlm.nih.gov/pubmed/38041016
http://dx.doi.org/10.1186/s12575-023-00222-1

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