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Range of chromatin accessibility configurations are permissive of GABAergic fate acquisition in developing mouse brain

In recent single-cell -omics studies, both the differential activity of transcription factors regulating cell fate determination and differential genome activation have been tested for utility as descriptors of cell types. Naturally, genome accessibility and gene expression are interlinked. To under...

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Detalles Bibliográficos
Autores principales: Kilpinen, Sami, Heliölä, Heidi, Achim, Kaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691053/
https://www.ncbi.nlm.nih.gov/pubmed/38036964
http://dx.doi.org/10.1186/s12864-023-09836-x