Dominant negative biologics normalise the tumour necrosis factor (TNF-α) induced angiogenesis which exploits the Mycobacterium tuberculosis dissemination

BACKGROUND: Tumor necrosis factor (TNF) is known to promote T cell migration and increase the expression of vascular endothelial growth factor (VEGF) and chemokines. The administration of Xpro-1595, a dominant-negative TNF (DN-TNF) engineered to selectively inactivate soluble TNF (solTNF), has been...

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Detalles Bibliográficos
Autores principales: Davuluri, Kusuma Sai, Singh, Amit Kumar, Yadav, Vimal Kumar, Singh, Ajay Vir, Singh, Shoor Vir, Chauhan, Devendra Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691138/
https://www.ncbi.nlm.nih.gov/pubmed/38036985
http://dx.doi.org/10.1186/s12865-023-00576-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691138/
https://www.ncbi.nlm.nih.gov/pubmed/38036985
http://dx.doi.org/10.1186/s12865-023-00576-x

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