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CSE triggers ferroptosis via SIRT4-mediated GNPAT deacetylation in the pathogenesis of COPD

BACKGROUND: It is now understood that ferroptosis plays a significant role in the progression of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke extract (CSE). However, the mechanisms underlying this relationship remain largely unclear. METHODS: In this study, we established...

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Detalles Bibliográficos
Autores principales: Li, Congping, Chen, Fei, Lin, Liangfen, Li, Jiwei, Zheng, Yamei, Chen, Qingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691148/
https://www.ncbi.nlm.nih.gov/pubmed/38041059
http://dx.doi.org/10.1186/s12931-023-02613-0