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In vivo antiangiogenic effect of nimbolide, trans-chalcone and piperine for use against glioblastoma

BACKGROUND: Angiogenesis is an important hallmark of Glioblastoma (GBM) marked by elevated vascular endothelial growth factor-A (VEGF-A) and its receptor 2 (VEGFR-2). As previously reported nimbolide (NBL), trans-chalcone (TC) and piperine (PPR) possess promising antiangiogenic activity in several c...

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Detalles Bibliográficos
Autores principales: Senrung, Anna, Tripathi, Tanya, Yadav, Joni, Janjua, Divya, Chaudhary, Apoorva, Chhokar, Arun, Aggarwal, Nikita, Joshi, Udit, Goswami, Nidhi, Bharti, Alok Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691152/
https://www.ncbi.nlm.nih.gov/pubmed/38036978
http://dx.doi.org/10.1186/s12885-023-11625-4