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Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes

OBJECTIVES: Osteoarthritis (OA) is a joint disease with a heritable component. Genetic loci identified via genome-wide association studies (GWAS) account for an estimated 26.3% of the disease trait variance in humans. Currently, there is no method for predicting the onset or progression of OA. We de...

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Detalles Bibliográficos
Autores principales: Kenny, Jacob, Mullin, Benjamin H., Tomlinson, William, Robertson, Brett, Yuan, Jinbo, Chen, Weiwei, Zhao, Jinmin, Pavlos, Nathan J., Walsh, John P., Wilson, Scott G., Tickner, Jennifer, Morahan, Grant, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691153/
https://www.ncbi.nlm.nih.gov/pubmed/38041181
http://dx.doi.org/10.1186/s13075-023-03216-2