TGF-β broadly modifies rather than specifically suppresses reactivated memory CD8 T cells in a dose-dependent manner

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Transforming growth factor β (TGF-β) directly acts on naive, effector, and memory T cells to control cell fate decisions, which was shown using genetic abrogation of TGF-β signaling. TGF-β availability is altered by infections and cancer; however, the dose-dependent effects of TGF-β on memory CD8 T...

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Detalles Bibliográficos
Autores principales: Taber, Alexis, Konecny, Andrew, Oda, Shannon K., Scott-Browne, James, Prlic, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691214/
https://www.ncbi.nlm.nih.gov/pubmed/37988468
http://dx.doi.org/10.1073/pnas.2313228120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691214/
https://www.ncbi.nlm.nih.gov/pubmed/37988468
http://dx.doi.org/10.1073/pnas.2313228120

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