Resistance gene–guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases

With the significant increase in the availability of microbial genome sequences in recent years, resistance gene–guided genome mining has emerged as a powerful approach for identifying natural products with specific bioactivities. Here, we present the use of this approach to reveal the roseopurpurin...

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Detalles Bibliográficos
Autores principales: Dunbar, Kyle L., Perlatti, Bruno, Liu, Nicholas, Cornelius, Amber, Mummau, Daniel, Chiang, Yi-Ming, Hon, Lawrence, Nimavat, Monika, Pallas, Jason, Kordes, Sina, Ng, Ho Leung, Harvey, Colin J. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691236/
https://www.ncbi.nlm.nih.gov/pubmed/37983497
http://dx.doi.org/10.1073/pnas.2310522120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691236/
https://www.ncbi.nlm.nih.gov/pubmed/37983497
http://dx.doi.org/10.1073/pnas.2310522120

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