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Resistance gene–guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases
With the significant increase in the availability of microbial genome sequences in recent years, resistance gene–guided genome mining has emerged as a powerful approach for identifying natural products with specific bioactivities. Here, we present the use of this approach to reveal the roseopurpurin...
Autores principales: | Dunbar, Kyle L., Perlatti, Bruno, Liu, Nicholas, Cornelius, Amber, Mummau, Daniel, Chiang, Yi-Ming, Hon, Lawrence, Nimavat, Monika, Pallas, Jason, Kordes, Sina, Ng, Ho Leung, Harvey, Colin J. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691236/ https://www.ncbi.nlm.nih.gov/pubmed/37983497 http://dx.doi.org/10.1073/pnas.2310522120 |
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