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Proteome-wide tagging with an H(2)O(2) biosensor reveals highly localized and dynamic redox microenvironments

Hydrogen peroxide (H(2)O(2)) sensing and signaling involves the reversible oxidation of particular thiols on particular proteins to modulate protein function in a dynamic manner. H(2)O(2) can be generated from various intracellular sources, but their identities and relative contributions are often u...

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Detalles Bibliográficos
Autores principales: Kritsiligkou, Paraskevi, Bosch, Katharina, Shen, Tzu Keng, Meurer, Matthias, Knop, Michael, Dick, Tobias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691247/
https://www.ncbi.nlm.nih.gov/pubmed/37991942
http://dx.doi.org/10.1073/pnas.2314043120