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Proteome-wide tagging with an H(2)O(2) biosensor reveals highly localized and dynamic redox microenvironments
Hydrogen peroxide (H(2)O(2)) sensing and signaling involves the reversible oxidation of particular thiols on particular proteins to modulate protein function in a dynamic manner. H(2)O(2) can be generated from various intracellular sources, but their identities and relative contributions are often u...
Autores principales: | Kritsiligkou, Paraskevi, Bosch, Katharina, Shen, Tzu Keng, Meurer, Matthias, Knop, Michael, Dick, Tobias P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691247/ https://www.ncbi.nlm.nih.gov/pubmed/37991942 http://dx.doi.org/10.1073/pnas.2314043120 |
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