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Mining toxicogenomic data for dose-responsive pathways: implications in advancing next-generation risk assessment

Introduction: While targeted investigation of key toxicity pathways has been instrumental for biomarker discovery, unbiased and holistic analysis of transcriptomic data provides a complementary systems-level perspective. However, in a systematic context, this approach has yet to receive comprehensiv...

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Detalles Bibliográficos
Autores principales: Barutcu, A. Rasim, Black, Michael B., Nong, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691261/
https://www.ncbi.nlm.nih.gov/pubmed/38046401
http://dx.doi.org/10.3389/ftox.2023.1272364