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Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence

During the COVID-19 pandemic we utilized an AI-driven T cell epitope prediction tool, the NEC Immune Profiler (NIP) to scrutinize and predict regions of T cell immunogenicity (hotspots) from the entire SARS-CoV-2 viral proteome. These immunogenic regions offer potential for the development of univer...

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Detalles Bibliográficos
Autores principales: Federico, Lorenzo, Malone, Brandon, Tennøe, Simen, Chaban, Viktoriia, Osen, Julie Røkke, Gainullin, Murat, Smorodina, Eva, Kared, Hassen, Akbar, Rahmad, Greiff, Victor, Stratford, Richard, Clancy, Trevor, Munthe, Ludvig Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691274/
https://www.ncbi.nlm.nih.gov/pubmed/38045681
http://dx.doi.org/10.3389/fimmu.2023.1265044