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Ubiquitin‐specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma

Ubiquitin‐specific protease 22 (USP22) has been identified as a potential marker for cancer stem cells in hepatocellular carcinoma (HCC). It can promote HCC stemness, which is considered a driver of tumorigenesis. Here, we sought to determine the role of USP22 in tumorigenesis, elucidate its underly...

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Detalles Bibliográficos
Autores principales: Ye, Qianwei, Zhou, Wei, Xu, Shengjun, Que, Qingyang, Zhan, Qifan, Zhang, Lincheng, Zheng, Shusen, Ling, Sunbin, Xu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691294/
https://www.ncbi.nlm.nih.gov/pubmed/38045832
http://dx.doi.org/10.1002/mco2.439