A human mesenchymal spheroid prototype to replace moderate severity animal procedures in leukaemia drug testing

Patient derived xenograft (PDX) models are regarded as gold standard preclinical models in leukaemia research, especially in testing new drug combinations where typically 45-50 mice are used per assay. 9000 animal experiments are performed annually in the UK in leukaemia research with these expensiv...

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Detalles Bibliográficos
Autores principales: Wilson, Aaron, Hockney, Sean, Parker, Jessica, Angel, Sharon, Blair, Helen, Pal, Deepali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691310/
https://www.ncbi.nlm.nih.gov/pubmed/38046539
http://dx.doi.org/10.12688/f1000research.123084.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691310/
https://www.ncbi.nlm.nih.gov/pubmed/38046539
http://dx.doi.org/10.12688/f1000research.123084.2

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