Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12

The TnpB proteins are transposon-associated RNA-guided nucleases that are among the most abundant proteins encoded in bacterial and archaeal genomes, but whose functions in the transposon life cycle remain unknown. TnpB appears to be the evolutionary ancestor of Cas12, the effector nuclease of type...

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Detalles Bibliográficos
Autores principales: Altae-Tran, Han, Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Kannan, Soumya, Zhang, Feng, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691335/
https://www.ncbi.nlm.nih.gov/pubmed/37983496
http://dx.doi.org/10.1073/pnas.2308224120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691335/
https://www.ncbi.nlm.nih.gov/pubmed/37983496
http://dx.doi.org/10.1073/pnas.2308224120

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