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Metabolically regulated spiking could serve neuronal energy homeostasis and protect from reactive oxygen species
So-called spontaneous activity is a central hallmark of most nervous systems. Such non-causal firing is contrary to the tenet of spikes as a means of communication, and its purpose remains unclear. We propose that self-initiated firing can serve as a release valve to protect neurons from the toxic c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691349/ https://www.ncbi.nlm.nih.gov/pubmed/37988463 http://dx.doi.org/10.1073/pnas.2306525120 |