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Metabolically regulated spiking could serve neuronal energy homeostasis and protect from reactive oxygen species

So-called spontaneous activity is a central hallmark of most nervous systems. Such non-causal firing is contrary to the tenet of spikes as a means of communication, and its purpose remains unclear. We propose that self-initiated firing can serve as a release valve to protect neurons from the toxic c...

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Detalles Bibliográficos
Autores principales: Chintaluri, Chaitanya, Vogels, Tim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691349/
https://www.ncbi.nlm.nih.gov/pubmed/37988463
http://dx.doi.org/10.1073/pnas.2306525120