GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

PURPOSE: This study aimed to explore the impact of GSK840 on retinal neuronal injury after retinal ischemia/reperfusion (IR) and its associated mechanism. METHODS: We established an in vivo mouse model of IR and an in vitro model of oxygen and glucose deprivation/reoxygenation (OGDR) in primary mous...

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Detalles Bibliográficos
Autores principales: Feng, Yanlin, Hu, Chenyang, Cui, Kaixuan, Fan, Matthew, Xiang, Wu, Ye, Dan, Shi, Yuxun, Ye, Huiwen, Bai, Xue, Wei, Yantao, Xu, Yue, Huang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691386/
https://www.ncbi.nlm.nih.gov/pubmed/38015174
http://dx.doi.org/10.1167/iovs.64.14.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691386/
https://www.ncbi.nlm.nih.gov/pubmed/38015174
http://dx.doi.org/10.1167/iovs.64.14.42

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