Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

PURPOSE: Diabetic retinopathy (DR) is a leading cause of blindness in working-age adults characterized by retinal dysfunction and neurovascular degeneration. We previously reported that deletion of X-box binding protein 1 (XBP1) leads to accelerated retinal neurodegeneration in diabetes; however, th...

Descripción completa

Detalles Bibliográficos
Autores principales: McLaughlin, Todd, Wang, Grant, Medina, Andy, Perkins, Jacob, Nihlawi, Rhudwan, Seyfried, Don, Hu, Zihua, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691399/
https://www.ncbi.nlm.nih.gov/pubmed/38015176
http://dx.doi.org/10.1167/iovs.64.14.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691399/
https://www.ncbi.nlm.nih.gov/pubmed/38015176
http://dx.doi.org/10.1167/iovs.64.14.40

Ejemplares similares