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Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy
PURPOSE: Diabetic retinopathy (DR) is a leading cause of blindness in working-age adults characterized by retinal dysfunction and neurovascular degeneration. We previously reported that deletion of X-box binding protein 1 (XBP1) leads to accelerated retinal neurodegeneration in diabetes; however, th...
Autores principales: | McLaughlin, Todd, Wang, Grant, Medina, Andy, Perkins, Jacob, Nihlawi, Rhudwan, Seyfried, Don, Hu, Zihua, Wang, Joshua J., Zhang, Sarah X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691399/ https://www.ncbi.nlm.nih.gov/pubmed/38015176 http://dx.doi.org/10.1167/iovs.64.14.40 |
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