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Clustered and diverse transcription factor binding underlies cell type specificity of enhancers for housekeeping genes

Housekeeping genes are considered to be regulated by common enhancers across different tissues. Here we report that most of the commonly expressed mouse or human genes across different cell types, including more than half of the previously identified housekeeping genes, are associated with cell type...

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Detalles Bibliográficos
Autores principales: Zhu, Iris, Landsman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691539/
https://www.ncbi.nlm.nih.gov/pubmed/37884340
http://dx.doi.org/10.1101/gr.278130.123