Knockout of Matrix Metalloproteinase 2 Opposes Hypertension- and Diabetes-induced Nephropathy

The progression of chronic kidney disease results from the accumulation of extracellular matrix leading to end-stage renal disease. We previously demonstrated that a broad-spectrum matrix metalloproteinase (MMP) inhibitor reduced renal injury in rat models of hypertension and diabetes. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirata, Takashi, Fan, Fan, Fan, Letao, Amin, Ghadir, White, Tiffani, Geurts, Aron M., Kojima, Naoki, Takahashi, Teisuke, Miyata, Noriyuki, Williams, Jan, Roman, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691661/
https://www.ncbi.nlm.nih.gov/pubmed/37643020
http://dx.doi.org/10.1097/FJC.0000000000001473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691661/
https://www.ncbi.nlm.nih.gov/pubmed/37643020
http://dx.doi.org/10.1097/FJC.0000000000001473

Ejemplares similares